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Tirzepatide vial of 60mg

What Is Tirz?

Tirzepatide is an research analog peptide to the glucose-dependent insulinotropic polypeptide (GIP). It is a novel peptide, Tirz is a synthetic derivative of gastric inhibitory polypeptide (GIP),Gastric inhibitory peptide (GIP) is a hormone produced by the duodenum and small intestine. It acts as an incretin and stimulates the production of insulin. Unlike GIP, which is made of 42 amino acids, Tirz has a modified amino acid chain consisting of 39 amino acids which are additionally lipidated to improve the peptides uptake into cells and its stability during metabolism.

Tirz as a peptide hormone ,that has the potential to act as an agonist at both the gastric inhibitory polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. The action of Tirzepatide (GIP) peptide is apparently mediated through activation of the GLP-1 and GIP receptors, possibly leading to enhanced insulin secretion, glucose uptake, and satiety signaling.

How Tirz Works ?

Tirz is a GIP receptor and GLP-1 receptor agonist. It is a 39-amino-acid modified peptide with a C20 fatty diacid moiety that enables albumin binding and prolongs the half-life. Made up of 39 amino acids, the relatively large Tirzepatide stimulates the release of insulin from the pancreas by binding to both GIP and GLP-1 (glucagon-like peptide-1) receptors. Tirzepatide selectively binds to and activates both the GIP and GLP-1 receptors, the targets for native GIP and GLP-1. The affinity of Tirzepatide for the GIP receptor is greater than its affinity for the GLP-1 receptor.